The Coagulation Cascade

coagulation cascade  The physiology of coagulation routes and paths is a cascade of several molecular phenomena and biological events which was classified into two categories The physiology of coagulation routes and paths is a cascade of several molecular phenomena and biological events which was classified into two categories

The coagulation cascade has significant limitations as a model of how hemostasis occurs in vivo, however This article describes how the modern view of Research into counteracting the tendency toward thrombosis has focused on inhibiting the factors involved in the cascade (tissue factor, factor X, prothrombin,

The coagulation cascade is useful to understand as it provides a framework for interpreting basic coagulation tests -the PT and APTT  The primary pathway for the initiation of blood coagulation is the tissue factor pathway Both the tissue factor and contact activation pathways